OWC Intros Slick Powerful Storage for Content Creators – Videoguys

OWC Intros Slick Powerful Storage for Content Creators – Videoguys

At Computex 2024, OWC showcased a variety of cutting-edge storage solutions for creators, as reported by btarunr for TechPowerUp. Renowned for their compatibility with Macs and iOS devices, OWC’s latest offerings are now standardized for both Macs and Windows PCs.

The OWC Thunderbolt Go Dock supports Intel’s new Thunderbolt Share standard, enabling a 40 Gbps network connection between two PCs or Macs. It facilitates sharing its ports, I/O, and card readers, including two downstream Thunderbolt 40 Gbps, HDMI display output, gigabit Ethernet, two 10 Gbps USB 3.2 Gen 2 type-A, a 10 Gbps USB 3.2 Gen 2 type-C, USB 2.0, HD audio with a 4-pole headset jack, and an SD card reader. The dock has its own internal power supply, driving all functions.

The Express 1M2 is a sleek, USB4-based portable SSD enclosure with an M.2-2280 slot featuring PCI-Express 3.0 x4 connection, achieving tested bandwidths up to 3151 MB/s. The aluminium enclosure, acting as a heatsink, supports up to 8 TB drives, starting at $249 for the 1 TB model.

OWC’s ThunderBlade X8 is a desktop portable SSD enclosure housing up to eight M.2-2242 SSDs, providing a total of 32 TB storage with RAID 0/1/4/5/1+0 configurations. In RAID 0, it offers sequential read speeds up to 2826 MB/s and write speeds up to 2949 MB/s. It features a 40 Gbps Thunderbolt 3 interface with two ports for daisy-chaining.

The Envoy Pro Elektron is the newest addition to the Envoy line, a portable SSD starting at $99.99 for the 240 GB model, and going up to 4 TB. It contains an M.2-2242 SSD with PCIe Gen 3 x2 connectivity and uses a 10 Gbps USB 3.2 Gen 2 bridge chip.

Finally, the Atlas USB4 CFexpress 4.0 Card Reader provides seamless connection to CFexpress 4.0 memory cards via a 40 Gbps USB4 interface. OWC also presented a range of SD, SDexpress, and CFexpress memory cards under the Atlas brand.

Read the full article by btarunr for TechPowerUp HERE

Prince Of Persia: The Sands Of Time Remake Is Coming In 2026

Prince Of Persia: The Sands Of Time Remake Is Coming In 2026

Prince of Persia: The Sands Of Time reemerged during Ubisoft’s Forward event, but only slightly. Basically, Ubisoft confirmed the game is still in development, but it won’t be releasing until 2026.

The game has hit some development difficulties over to course of its creation. When announced, Ubisoft Pune and Ubisoft Mumbai were said to be developing the game, but in 2022 it was shared that development duties would be handed over to Ubisoft Montreal. It seems at that time development was effectively fully reset because it will be some time before release.

For more on Prince of Persia: The Sands of Time remake, head here. For a look at the original game, you can check out our recent episode or Replay below.

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An Into The Spider-Verse Costume And More Are Coming To Spider-Man 2 Later This Month

Marvel’s Spider-Man 2 is getting an update on June 18 that “addresses some community feedback and adds stability improvements to the game,” but the more exciting detail is the addition of eight new suits, one of which is in reference to the Spider-Verse films.

A suit inspired by Peter B. Parker’s look will be available for Peter Parker, seen below, although it does lack his telltale gut. The other seven suits, which can be seen on PlayStation’s blog, have been created by guest designers KidSuper, Vini Jr, Lando Norris, and Rina Sawayama. There are also a few suits referencing specific Spider-Man lore, and a new Mile Morales suit (seen above) that “is reminiscent of classic cartoons and comics of old.”

An Into The Spider-Verse Costume And More Are Coming To Spider-Man 2 Later This Month

For more on the web-slinger latest video game adventure, you can read Game Informer‘s Marvel’s Spider-Man 2 review here.

Arcane Season 2, Which Will Be The Final Chapter, Gets A New Teaser Trailer Ahead Of November Premiere

Arcane Season 2, Which Will Be The Final Chapter, Gets A New Teaser Trailer Ahead Of November Premiere

Netflix had released a new trailer for Season 2 of Arcane, the hit animated series set in the League of Legends universe. Set to premiere in November, show creators Christian Linke and Alex Yee confirm the upcoming season will be the show’s last.

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Season 2 is billed as “the final chapter” and will center on Jinx’s attack on the Council, which will be the centerpiece of the escalating Piltover/Zaun conflict. Hailee Steinfeld (Vi) and Ella Purnell (Jinx) will reprise their roles in Season 2. While Arcane will conclude, Christian Link stated during a League of Legends dev update today that it won’t be the last animated tale based on the franchise. 

Arcane is just the beginning of our larger storytelling journey and partnership with the wonderful animation studio that is Fortiche,” said Linke. “From the very beginning, since we started working on this project, we had a very specific ending in mind, which means the story of Arcane wraps up with this second season. But Arcane is just the first of many stories that we want to tell in Runeterra.”

You can watch the first teaser for Arcane Season 2 here. For more on League of Legends, check out our in-depth preview of 2XKO, the franchise’s upcoming fighting game. 

San Francisco 49ers’ Christian McCaffrey Graces Madden NFL 25 Cover

San Francisco 49ers’ Christian McCaffrey Graces Madden NFL 25 Cover

Madden NFL 25 (the new one, not the bizarrely titled 25th-anniversary entry of the same name from 2013) has found its cover athlete. Hot off his run to a near-victory in Super Bowl LVIII comes San Francisco 49er running back Christian McCaffrey.

The reigning NFL Offensive Player of the Year will grace the standard and Deluxe Editions. You can view both covers in the gallery below.

EA has yet to detail Madden 25’s gameplay but teases the next evolution of current-gen/PC exclusive features such as FieldSense, new commentary and presentation, and updates to Franchise and other modes. A press release states EA plans to announce gameplay details “soon.” 

Madden NFL 25 launches on August 16 for PlayStation 5, Xbox Series X/S, PlayStation 4, Xbox One, and PC. You can read our review of last year’s Madden NFL 24 here. For the first time in years, Madden won’t be EA’s only licensed football sim this year, as EA Sports College Football makes its comeback on July 19. You can watch the first trailer here

Bob Prior: A deep legacy of cultivating books at the MIT Press

Bob Prior: A deep legacy of cultivating books at the MIT Press

In his first years as an acquisitions editor at the MIT Press in the late 1980s, Bob Prior helped handle a burgeoning computer science list.

Thirty-six years later, Prior has edited hundreds of trade and scholarly books in areas as diverse as neuroscience, natural history, electronic privacy, evolution, and design — including one single novel that he was able to sneak onto his list of otherwise entirely nonfiction titles. In more recent years as executive editor for biomedical science, neuroscience, and trade science, his work has focused on general interest science books with an emphasis on the life sciences, neuroscience, and natural history.

Prior argues, though, that his work — while fundamentally remaining the same — has always felt keenly different from year to year. “You utilize the same kind of skills, but in service of very different authors and very different projects,” he says.

And after a career at the press spanning three-plus decades, Prior is set to retire at the end of June.

He will leave behind an incredible legacy — especially as “a master networker, an astute acquiring editor, and a champion of rigorous and brilliant scholarship,” says Bill Smith, director of sales and marketing at the MIT Press. “His curious mind is always on the lookout for brilliant scientists and authors who have something to say to the wider world.”

“I’ve always valued his excellent instincts and competitive drive as an acquisitions editor, and his passion for his work and for the research in the fields that he works on,” says Amy Brand, director and publisher of the press. “In recent years, he’s been very generous in providing astute guidance to me and other press colleagues on specific projects and our overall acquisitions program.”

“Best of all, Bob is a boundary pusher, constantly questioning the preconceptions of what a smart, general reader book can be,” says Smith.

For Prior, some of his favorite projects over his career at the press have been some of the most personal.

One of the books he is proudest of having worked on is “The Autobiography of a Transgender Scientist,” written by lauded neuroscientist Ben Barres and finished just prior to his death from pancreatic cancer in 2017. Prior was tasked with editing Barres’s book posthumously.

“It is an incredibly personal story; he talks about his experiences being an undergrad at MIT, his transition, and the challenges of his life,” says Prior. With the diligent care that is a hallmark of Prior’s work as an editor, he helped bring Barres’s final work to the public eye. “It’s a book I am very proud of because of Ben’s legacy and the person he was, and because every person I know who has read it has been transformed by it in some way,” Prior says. “The book has strongly impacted my view of the world.”

Other books acquired by Prior over the course of his career include “The Laws of Simplicity,” by John Maeda; “The Distracted Mind: Ancient Brains in a High-Tech World,” by Adam Gazzaley and Larry D. Rosen; “Consciousness: Confessions of a Romantic Reductionist,” by Christof Koch; “Blueprint: How DNA Makes Us Who We Are,” by Robert Plomin; and “The Alchemy of Us: How Humans and Matter Transformed One Another,” by Ainissa Ramirez.

According to Gita Manaktala, executive editor at large at the MIT Press, Prior’s dedication and incredible success throughout his career is no coincidence. “For nearly 40 years, Bob Prior has shown us how to cultivate books by scientists and technologists,” Manaktala says. Each week Prior writes to a list of people he has never met but whose work he admires. Sometimes he hears back; but just as often he does not, Manaktala says — or at least not right away. Even so, Prior has never given up, knowing that books and relationships take time and effort to build.

“His sustained interest in people, ideas, and their impact on the world is what makes a great editor,” Manaktala adds. “Bob has helped to grow hundreds of essential books from small seeds. The world of ideas is a richer, greener, and more fertile place for his efforts.”

“I’ll personally miss him and his insights a great deal,” says Brand.

“While my life after MIT Press will be full with family, friends, and meaningful work in my community, I will definitely miss the world of publishing and chasing down great authors,” Prior says of his 36 years at the press. “What I will miss the most are my incredible colleagues; what an amazing place to make a career.”

Talon AV’s Sky-High Success with Epiphan Pearl: Revolutionizing Remote – Videoguys

Talon AV’s Sky-High Success with Epiphan Pearl: Revolutionizing Remote – Videoguys

Small Company, Big Impact in Video Production

Talon AV, a video production company, excels in providing top-notch video streaming, recording, and production services for live events. From corporate webinars to multi-day conferences with multiple breakout rooms, their efficiency enables them to manage multiple concurrent events, making a significant impact despite being a small team.

How Talon AV Manages Remote Event Production with Epiphan Pearl

To overcome the challenge of being in multiple places simultaneously, Talon AV’s CEO, Tim Kerbavaz, turned to Epiphan’s Pearl systems. These systems are renowned for their flexibility, reliability, and, most importantly, remote control capabilities. By deploying Pearl systems on-site and connecting them to the network, Talon AV can oversee multiple events from any location. Remarkably, they have even managed live streaming sessions from an airplane. This is all made possible through Epiphan Edge™, which facilitates remote production and monitoring of Pearl systems from anywhere.

Scaling Operations with Remote Event Support

The ability to manage multiple devices remotely has allowed Talon AV to expand its services beyond a single site. They now offer remote event support services, enabling the team to handle several events simultaneously. This scalability has significantly boosted their operations without the need for a larger physical footprint.

Key Benefits of Using Epiphan Pearl and Edge for Remote Event Management

  1. Remote Management: With Epiphan Edge, Talon AV can remotely monitor and control Pearl devices, make real-time adjustments, and manage file workflows from various locations. This capability is a game-changer for events spanning multiple rooms or locations.

  2. Versatile Streaming and Recording: Pearl’s adaptability ensures high-quality video delivery under different network conditions and requirements. Whether it’s direct streaming or point-to-point SRT links, Talon AV can handle diverse show needs with one set of hardware.

  3. Large-Scale Event Management: For events with multiple breakout rooms, Pearl hardware facilitates efficient management and recording. It meets strict security requirements while maintaining a compact operational footprint, proving indispensable for capturing content in large-scale events.

Conclusion: Talon AV’s Success Story with Epiphan Pearl

For Talon AV, Epiphan’s Pearl and Edge are indispensable tools in their event production arsenal. These products have enabled Tim and his team to tackle the challenges of live event production head-on. The reliability and flexibility of Epiphan products have not only streamlined Talon AV’s operations but also significantly boosted the company’s image.

By managing more clients and multiple events simultaneously, Talon AV has set itself apart in the industry. Their ability to achieve more with fewer resources has enhanced their reputation for efficiency and excellence, making every event a success story.

Explore how Epiphan Pearl and Epiphan Edge can revolutionize your remote event production, just like they did for Talon AV.


Citizen Sleeper 2: Starward Vector Preview – On The Run, Again – Game Informer

Citizen Sleeper took me by surprise in 2022, giving me a rare new video game experience, both mechanically and narratively, and my dice-centric role-playing adventure has stuck with me since. I still think about my Sleeper and what they’re up to now. In a year where Elden Ring didn’t release, it would have been my game of the year with a bullet – read my Citizen Sleeper review here to find out why. Now, a little more than two years later, I’ve played parts of the opening hour of Citizen Sleeper 2: Starward Vector and find myself desperate to play more. It brings back its incredible sci-fi score, cyberpunk (yet distinct) visual style, and thought-provoking and stress-inducing writing. It infuses everything I love about the first Citizen Sleeper with new mechanics that fuel the game’s central decision-making processes. 

Like the first game, I assign my Sleeper one of three classes. I go with the Operator, which the game describes as physically fragile but great at working in interfaces and computer systems. Immediately, I notice the selected class plays a more significant role in how your experience will play out because the Operator lacks access to an entire skill. This means I’m automatically at a disadvantage with any action requiring said skill. However, I have access to the Reboot skill that allows me to reset my system, which mechanically means I gain a dice reroll. It’s a risky skill, as I could roll an even lower number, putting whatever action is at hand further into jeopardy. I could also roll a significantly better number, too, though. 

Citizen Sleeper 2: Starward Vector Preview – On The Run, Again – Game Informer

The story picks up after my Sleeper has been helped by their friend Serafin. I’ve recently rebooted my entire system, ending my dependence on the Stabilizer drug that plays a major role in Citizen Sleeper and the gang leader Laine, who supplies it to me. It’s these types of touchstones to the first game players will find in the sequel, which is its own standalone story. However, the reboot was just a partial success. Sure, I no longer need Stabilizer, but my artificial body is malfunctioning. Serafin and I flee on a ship called the Rig, which we steal from Laine and take to Hexport. 

Citizen Sleeper 2: Starward Vector Hands-On Preview Gameplay Story narrative

Laine, unhappy with everything we’ve done, is after us by way of gang members, bounties, and more. He’s someone my Sleeper once saw as a protector, a savior even, but now, they know him as “a pursuer, a tormentor, a nightmare.” I can’t help but notice the setup for Citizen Sleeper 2 is nearly identical to the first game – a Sleeper whose body is fighting against them is on the run from someone bigger than them. Gareth Damian Martin, the sole developer at one-person studio Jump Over The Age (though Martin has some help in developing Citizen Sleeper 2), says that’s intentional. 

“I’m a big fan of noir storytelling,” Martin tells me. “I guess it’s a bit of old-fashioned storytelling, but I like the idea about an ordinary person who’s getting sucked into extraordinary circumstances trying to improvise their way through it.”

They say they wanted to change it up a bit for the sequel – instead of running from a corporate conglomerate, you’re running from a singular person and his gang of underlings. Martin says they feel the result is a story that’s a “bit more intimate and intimidating, and in a way, weirdly scarier because it feels a little more dangerous.” 

Citizen Sleeper 2: Starward Vector Hands-On Preview Gameplay Story narrative

Laine

After selecting my Sleeper, I’m thrown right into the dice action that returns from the first game. Serafin is going to check on something, so they task me with going to the Hexport Docks to pick up some small gigs. I put a 5-dice (the higher the number, the more likely the action I assign the dice to ends up with a positive outcome versus a neutral or costly negative one) on a “Chat to Crews” function here to get some tips on potential crew recruits and contacts. However, despite the high positive chance with a 5-dice, I get a neutral outcome and only get material. From here, I explore the area more and eventually unveil a new location after completing enough actions at a different spot. It’s “The Bends,” and I can gamble some Cryo (currency) in the Star and Stoker game or buy some fries to restore my energy. 

You lose one segment from your energy bar for each cycle or day of action (largely determined by your running out of dice). If this bar is empty, you starve and gain one stress bar per cycle. It’s here I learn Martin has taken a recurring feeling from the first game – the stress one experiences while playing and its effect on your decision-making – and turned it into an actual in-game mechanic aptly named stress. This dictates how much damage your dice will take when rolled. Damage a dice three times, and it breaks until it’s fixed. 

Citizen Sleeper 2: Starward Vector Hands-On Preview Gameplay Story narrative

Stress joins another new mechanic called Glitch, which I don’t experience in my hands-on demo but witness in a hands-off preview played by Martin. If you roll your dice while you have some Glitch, which, like Stress, is represented in the U.I., you can roll Glitch dice. These have an 80% chance for a negative outcome but a 20% chance for the best possible outcome, once more playing into the risk-and-reward feel permeating the game. You gain Glitch based on how you repair or heal your body – scrap parts might yield more Glitch, whereas more premium resources yield little to none. Together, these mechanics add an exciting but stressful new layer to each decision you make with dice. 

“When you look up there [at your U.I. bar], there’s this kind of game of plates spinning,”  Martin tells me. “The big part of those plates is actually you dealing with the facilities and capabilities of your body. Even when you heal one of your dice slots, you’re having to deal with the fact that you’re taking on Glitch, and therefore, you’ve got to think about, ‘Do I go on a job right now when I’ve got this level of Glitch or do I rest a bit?’ In general, this is connected to me adding a bit more mechanical heft to the game, especially when it comes to players who aren’t necessarily drawn to the role-playing without some kind of mechanical support for that.” 

Citizen Sleeper 2: Starward Vector Hands-On Preview Gameplay Story narrative

Martin hopes these additional layers of mechanics provide new pathways for role-playing. With Citizen Sleeper, they noticed some players would lean into the role-playing aspect, making money and decisions based on how their Sleeper might. However, some players said, “I like to make money wherever I make the most money.” It was strictly mechanical for them. 

“I always felt like, ‘Oh, that’s a shame because I want you to engage with this character that you’re playing and the story they’re telling,’ so this time around, if I want players to think about how they have to deal with something, there’s a mechanical effect,” Martin says. 

As there’s no point in spoiling the narrative events that transpire in this preview build, given how narrative-focused the series is, I’m going to jump ahead to another new mechanic: Contracts. After picking one up at the Hexport contract board, I learn these high-risk, high-reward jobs greatly expand the scope of Citizen Sleeper 2. Unlike the first game, which primarily takes place on a singular space station called the Eye, Citizen Sleeper 2 gives players access to a large star map with various points of interest. 

Citizen Sleeper 2: Starward Vector Hands-On Preview Gameplay Story narrative

Before embarking on this contract, the game warns me to ensure I have enough fuel to travel to the contract, supplies to keep my Sleeper and crew going, and that I take the opportunity to scout out new freelance crew members to join. Your crew plays a significant role both in the main narrative of Citizen Sleeper 2 and these contracts, which Martin describes as vignettes or episodes inspired by, for example, sub-arcs in series like Firefly, Cowboy Bebop, or other sci-fi greats. They say you might do two or three contracts and see the same character repeatedly, or there might be contracts where you meet a character for the first and last time. Regardless, it’s about the “little story” you get from these contracts. Some are high intensity, others are more laid back, Martin says. The one I do in my preview falls into the former. 

After traversing across space to a security drone with something inside I need, I learn that said drone is rigged to blow. Four mistakes and the contract could be over on account of an explosion. As such, I must disable parts of the drone in a semi-sequential order while maintaining a balancing act of dice, supplies (and energy), and more. Supplies, of which I can carry a maximum of five at this point and do before leaving for this contract, automatically replenish energy after each cycle during a contract. When you run out of supplies, your energy will deplete each cycle, and as your energy depletes, your dice get worse, jeopardizing the mission at hand. That’s why preparing ahead of time for a contract is essential. 

Citizen Sleeper 2: Starward Vector Hands-On Preview Gameplay Story narrative

However, with a drone rigged to blow after four mistakes, I can’t risk using low-number dice with high chances of failure or my low-number crew dice, which, like mine, take into effect our skill proficiencies and can be used alongside my own Sleeper’s dice. Not wanting to risk the low-number dice, I end cycles prematurely, crossing my fingers that I roll some higher-number dice the next day. Fortunately, I do and complete the contract. Some intriguing story stuff happens when I return to Hexport that I won’t spoil here, and my demo is over. 

During the preview Martin plays, I see even more of the mechanical and narrative synergy (and stress) of Citizen Sleeper 2 at play. You can utilize Push to get dice bonuses, but doing so immediately adds to your Stress meter. The skill tree is more expansive and customizable, designed with freedom in mind rather than guiding players toward a specific build. Everything I see excites me. 

Martin says they’re halfway through developing the game and already at 120,000 words – Citizen Sleeper and its DLC totals 180,000 words, promising a rich storytelling experience in the sequel. There’s a larger push from Martin to lean into Citizen Sleeper’s tabletop inspirations and its cyberpunk themes. Citizen Sleeper 2 is, on paper, a classic example of more story, more systems, more to do. But critically, Martin isn’t just going bigger, instead carefully curating an experience that strikes sharply at the heart of what made the first game work so well: the oh-so-fine balance between success and failure and the stress that lives between the two. If the heart-pumping I felt during my hour with the game is any indication, Martin has rolled a strong set of dice in this first preview cycle for this sequel.

Symposium highlights scale of mental health crisis and novel methods of diagnosis and treatment

Symposium highlights scale of mental health crisis and novel methods of diagnosis and treatment

Digital technologies, such as smartphones and machine learning, have revolutionized education. At the McGovern Institute for Brain Research’s 2024 Spring Symposium, “Transformational Strategies in Mental Health,” experts from across the sciences — including psychiatry, psychology, neuroscience, computer science, and others — agreed that these technologies could also play a significant role in advancing the diagnosis and treatment of mental health disorders and neurological conditions.

Co-hosted by the McGovern Institute, MIT Open Learning, McClean Hospital, the Poitras Center for Psychiatric Disorders Research at MIT, and the Wellcome Trust, the symposium raised the alarm about the rise in mental health challenges and showcased the potential for novel diagnostic and treatment methods.

John Gabrieli, the Grover Hermann Professor of Health Sciences and Technology at MIT, kicked off the symposium with a call for an effort on par with the Manhattan Project, which in the 1940s saw leading scientists collaborate to do what seemed impossible. While the challenge of mental health is quite different, Gabrieli stressed, the complexity and urgency of the issue are similar. In his later talk, “How can science serve psychiatry to enhance mental health?,” he noted a 35 percent rise in teen suicide deaths between 1999 and 2000 and, between 2007 and 2015, a 100 percent increase in emergency room visits for youths ages 5 to 18 who experienced a suicide attempt or suicidal ideation.

“We have no moral ambiguity, but all of us speaking today are having this meeting in part because we feel this urgency,” said Gabrieli, who is also a professor of brain and cognitive sciences, the director of the Integrated Learning Initiative (MITili) at MIT Open Learning, and a member of the McGovern Institute. “We have to do something together as a community of scientists and partners of all kinds to make a difference.”

An urgent problem

In 2021, U.S. Surgeon General Vivek Murthy issued an advisory on the increase in mental health challenges in youth; in 2023, he issued another, warning of the effects of social media on youth mental health. At the symposium, Susan Whitfield-Gabrieli, a research affiliate at the McGovern Institute and a professor of psychology and director of the Biomedical Imaging Center at Northeastern University, cited these recent advisories, saying they underscore the need to “innovate new methods of intervention.”

Other symposium speakers also highlighted evidence of growing mental health challenges for youth and adolescents. Christian Webb, associate professor of psychology at Harvard Medical School, stated that by the end of adolescence, 15-20 percent of teens will have experienced at least one episode of clinical depression, with girls facing the highest risk. Most teens who experience depression receive no treatment, he added.

Adults who experience mental health challenges need new interventions, too. John Krystal, the Robert L. McNeil Jr. Professor of Translational Research and chair of the Department of Psychiatry at Yale University School of Medicine, pointed to the limited efficacy of antidepressants, which typically take about two months to have an effect on the patient. Patients with treatment-resistant depression face a 75 percent likelihood of relapse within a year of starting antidepressants. Treatments for other mental health disorders, including bipolar and psychotic disorders, have serious side effects that can deter patients from adherence, said Virginie-Anne Chouinard, director of research at McLean OnTrackTM, a program for first episode psychosis at McLean Hospital.

New treatments, new technologies

Emerging technologies, including smartphone technology and artificial intelligence, are key to the interventions that symposium speakers shared.

In a talk on AI and the brain, Dina Katabi, the Thuan and Nicole Pham Professor of Electrical Engineering and Computer Science at MIT, discussed novel ways to detect Parkinson’s and Alzheimer’s, among other diseases. Early-stage research involved developing devices that can analyze how movement within a space impacts the surrounding electromagnetic field, as well as how wireless signals can detect breathing and sleep stages.

“I realize this may sound like la-la land,” Katabi said. “But it’s not! This device is used today by real patients, enabled by a revolution in neural networks and AI.”

Parkinson’s disease often cannot be diagnosed until significant impairment has already occurred. In a set of studies, Katabi’s team collected data on nocturnal breathing and trained a custom neural network to detect occurrences of Parkinson’s. They found the network was over 90 percent accurate in its detection. Next, the team used AI to analyze two sets of breathing data collected from patients at a six-year interval. Could their custom neural network identify patients who did not have a Parkinson’s diagnosis on the first visit, but subsequently received one? The answer was largely yes: Machine learning identified 75 percent of patients who would go on to receive a diagnosis.

Detecting high-risk patients at an early stage could make a substantial difference for intervention and treatment. Similarly, research by Jordan Smoller, professor of psychiatry at Harvard Medical School and director of the Center for Precision Psychiatry at Massachusetts General Hospital, demonstrated that AI-aided suicide risk prediction model could detect 45 percent of suicide attempts or deaths with 90 percent specificity, about two to three years in advance.

Other presentations, including a series of lightning talks, shared new and emerging treatments, such as the use of ketamine to treat depression; the use of smartphones, including daily text surveys and mindfulness apps, in treating depression in adolescents; metabolic interventions for psychotic disorders; the use of machine learning to detect impairment from THC intoxication; and family-focused treatment, rather than individual therapy, for youth depression.

Advancing understanding

The frequency and severity of adverse mental health events for children, adolescents, and adults demonstrate the necessity of funding for mental health research — and the open sharing of these findings.

Niall Boyce, head of mental health field building at the Wellcome Trust — a global charitable foundation dedicated to using science to solve urgent health challenges — outlined the foundation’s funding philosophy of supporting research that is “collaborative, coherent, and focused” and centers on “What is most important to those most affected?” Wellcome research managers Anum Farid and Tayla McCloud stressed the importance of projects that involve people with lived experience of mental health challenges and “blue sky thinking” that takes risks and can advance understanding in innovative ways. Wellcome requires that all published research resulting from its funding be open and accessible in order to maximize their benefits. 

Whether through therapeutic models, pharmaceutical treatments, or machine learning, symposium speakers agreed that transformative approaches to mental health call for collaboration and innovation.

“Understanding mental health requires us to understand the unbelievable diversity of humans,” Gabrieli said. “We have to use all the tools we have now to develop new treatments that will work for people for whom our conventional treatments don’t.”